B vitamins have been shown in a variety of studies to be important for the brain, low levels have been linked to poor memory, depression, cognition (memory function) and Alzheimers’s disease – for my previous articles please read here In older individuals, especially those who are suffering from cognitive (brain function) decline, there is often an increased rate of brain wastage/shrinking (atrophy). Previous studies have found that homocysteine is a risk factor for brain atrophy, cognitive impairment and dementia. It is also known that blood plasma concentrations of homocysteine can be lowered by dietary administration of B vitamins. Homocysteine is produced when the amino acid (the building blocks of protein) methionine is broken down in the body. Normal levels of homocysteine are important to help build and maintain body tissues, however elevated concentrations in the blood can be harmful and have been associated with an increased risk of heart disease and other disorders. At normal levels homocystein can be converted in the body into a harmless substance called cystanthionine. The conversion of homocysteine into this harmless substance depends upon various B vitamins (B6, B12 and folic acid). Having good levels of these B vitamins appears to be a very good way of preventing high homocysteine levels and low levels of B vitamins have been associated with raised homocysteine levels. The evidence, however is still controversial. A newly published study (1) has found that low vitamin B12 levels may lead to brain shrinkage (reduced brain….